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Request Appointment. Thyroid peroxidase antibody test: What is it? Products and services. What is a thyroid peroxidase antibody test? Does it diagnose thyroid disease? Answer From Todd B. With Todd B. Thank you for Subscribing Our Housecall e-newsletter will keep you up-to-date on the latest health information.
Please try again. After the procedure, the elastic band is removed. Once the blood has been collected, the needle is removed and the area is covered with cotton or a bandage to stop the bleeding.
Collecting the blood for the test will only take a few minutes. Collecting blood for this test will only take a few minutes. Collecting a blood sample is only temporarily uncomfortable and can feel like a quick pinprick. Afterward, there may be some mild bruising, which should go away in a day or so. The blood sample will be processed by a machine.
The results are commonly available after a few days. The thyroid peroxidase antibodies test is considered a safe procedure. However, as with many medical tests, some problems can occur with having blood drawn, such as:. Having a blood test is relatively painless. Still, many kids are afraid of needles. Explaining the test in terms your child can understand might help ease some of the fear.
Values above 9. In patients with subclinical hypothyroidism, the presence of thyroperoxidase TPO antibodies predicts a higher risk of developing overt hypothyroidism, 4. Furthermore, it raises the concern that such patients may be at increased risk of developing other autoimmune diseases, such as adrenal insufficiency and type 1 diabetes. There is a good association between the presence of autoantibodies against TPO and histological thyroiditis.
However, in view of the extensive regenerative capacity of the thyroid under the influence of thyroid-stimulating hormone, chronic thyroid disease may be present for years before the clinical manifestation of hypothyroidism becomes evident, if ever. Moderately increased levels of thyroperoxidase TPO antibodies may be found in patients with non-thyroid autoimmune disease such as pernicious anemia, type I diabetes, or other disorders that activate the immune system.
Some patients who have been exposed to animal antigens, either in the environment or as part of treatment or imaging procedure, may have circulating anti-animal antibodies present.
These antibodies may interfere with the assay reagents to produce unreliable results. Feldt-Rasmussen U: Analytical and clinical performance goals for testing autoantibodies to thyroperoxidase, thyroglobulin, and thyrotropin receptor.
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