Why deuterated solvents

We get the volume of D 2 O in L, by dividing the mass, 60 g D 2 O, by the mass of one liter, to get 0. Assuming the NaOD occupies no additional volume in the solution, the volume of D 2 O is equal to the volume of the solution.

Dividing 0. We have assumed that slight variations of MW due to isotopic enrichment, and density variations with temperature can be ignored.

Some of the benefits of participation in this program include a credit to your CIL account. To learn more about this program, please contact your customer service representative at North America or International. D euterated Solvents. NMR Reference Standards. NMR Tubes. Deuterated Buffers. Click here to learn more. Cambridge Isotope Labs Search Login. Avoiding CO2 in Catalysis of Decarboxylation. Investigation of the influence of the dielectric and electron-donor properties of solvents on the hydrogen bonds of?

Journal of Applied Spectroscopy , 29 1 , Ignacz , Nick Serpone. Journal of Organometallic Chemistry , 3 , Franchuk , L. Hydrogen bonds in solutions of salts of the N-oxide of? Theoretical and Experimental Chemistry , 10 5 , Stereochemistry of, and kinetics of environmental averaging processes in some organogermanium IV and organosilicon IV chelates.

Journal of Organometallic Chemistry , 84 2 , Baker , T. Solvent stabilization of conformers in o-iodophenol. Spectrochimica Acta , 22 1 , Pair your accounts. Your Mendeley pairing has expired. Please reconnect. Similarly, deuterated acetone, or acetone- d 6 , can be prepared as follows 4 :.

Figure 3. Reaction scheme for the preparation of acetone- d 6 from acetone and excess deuterium oxide in the presence of deuterated lithium hydroxide. These types of transformations typically require multiple steps, wherein the same reaction is repeated with further enrichment occurring over time.

While using D 2 O to prepare other deuterated solvents is a very useful method, many solvents are prepared using transition metals catalysts. These reactions often proceed via C-H bond activation by the metal, often coupled with either activation of C-D bonds or D 2 gas, and terminating in C-D bond formation, leading to the desired products.

Unfortunately, most industrial processes currently in-use to produce most common deuterated solvents used in NMR today are proprietary and the full details of these techniques are not public knowledge. Figure 4. Proton lock as opposed to deuterium lock can easily be selected on the Nanalysis benchtop NMR instrument by selecting the highlighted box and choosing the appropriate solvent from the box beside it.

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